Occult hepatitis B virus infection: diagnosis, implications and management?

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CHARACTERISTICS AND PREVALENCE OF OCCULT HEPATITIS B VIRUS INFECTION IN PATIENTS WITH HEPATITIS C IN IRAN

 ABSTRACT Background: Hepatitis B virus (HBV) infection in patients who lack detectable hepatitis B surface antigen (HBsAg) is called occult hepatitis B infection. Such infections have been frequently identified in patients with chronic hepatitis Cliver disease, but their prevalence is not known. Methods: 207 patients with chronic hepatitis C who were HCV -RNA and antiHCV positive were stu...

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Occult hepatitis B virus infection: implications in transfusion.

Hepatitis B virus (HBV) presents a higher residual risk of transmission by transfusion than hepatitis C virus (HCV) or human immunodeficiency virus (HIV). While most infectious blood units are removed by screening for hepatitis B surface antigen (HBsAg), there is clear evidence that transmission by HBsAg-negative components occurs, in part, during the serologically negative window period, but m...

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Diagnosis and Management of Occult Hepatitis B Virus Infection: a Short Review

Occult hepatitis B virus infection (OBI) is a challenging clinical entity. It is defined as the presence of viral DNA in the liver or serum of subjects who test negative for the hepatitis B surface antigen. Molecular evidence of OBI consists of covalently closed circular DNA persisting in the nuclei of hepatocytes after infection. Immunocompetent individuals have a lower risk of complications t...

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Update on occult hepatitis B virus infection

The event of mutations in the surface antigen gene of hepatitis B virus (HBV) results in undetectable hepatitis B surface antigen with positive/negative anti-hepatitis B core (anti-HBc) antibody status in serum and this phenomenon is named occult hepatitis B infection (OBI). The presence of anti-HBc antibody in serum is an important key for OBI tracking, although about 20% of OBI cases are nega...

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Occult Hepatitis B Virus Infection in Chronic Hemodialysis Patients in Panje-Azar Hospital, Gorgan

Abstract Background and objectives: Hepatitis B virus infection is a major health problem in worldwide. The prevalence of Occult and chronic HBV in hemodialysis patients is higher than standard in developing countries. People with occult HBV are negative for HBV surface antigen (HBsAg) but positive for HBV-DNA. We aimed to evaluate occult hepatitis B infection in patients under hemodialysis in ...

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ژورنال

عنوان ژورنال: Journal of Gastroenterology and Hepatology

سال: 2004

ISSN: 0815-9319,1440-1746

DOI: 10.1111/j.1440-1746.2004.03657.x